For many of us the St. John's wort brings images of beautiful yellow flower. It looks like the old herbalists were more focused on its perforated leaves. According to the legend the little 'holes' were caused by the devil who was jealous of the healing power of the herb. This explains the coloring of the leaves in VMS f1v and the 'devil's foot'-like root of the plant.
The Morgan Library Dioscorides drawing of St. John's wort is inscribed 'androsaimom'. Hypericum androsaemum's fruit is a black berry (it starts white, turns green, red and finally goes black). The fruit is known as Tutsan berry. Compared to the Belladonna we see St. John's wort is closer to the VMS f1v, because the surrounding cup leaves are round. Atropa's are star-like sharp.
UPDATE: Sarah Goslee noted that the earliest known drawing of Atropa Belladonna (Barsines) is found in Les Grandes Heures d'Anne de Bretagne illuminated between 1503 and 1508 (BNF Latin 9474 here )